BDBM288911 US10092563, Compound 47
SMILES Fc1ccc(Cl)c2c1nc([C@@H](Nc1ncnn3ccnc13)C1CC1)n(N1CCNCC1)c2=O
InChI Key InChIKey=BYGVWEJVJOISHG-INIZCTEOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288911
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: >1.00E+7nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair